Metastate Brain program
Rank synthetic lethal hypotheses and make validation minimal.
Synthetic lethality fails in practice when teams generate too many weak hypotheses and validate randomly. This program produces a ranked hypothesis set with clear rationale and a validation plan designed to resolve the decision fast.
Interpretable hypotheses, minimal validation plan.
Who it's for
- Functional genomics and discovery groups.
- Teams with screening data that is noisy or contradictory.
- Teams who need interpretable next experiments.
What you get
- Ranked interaction hypotheses with evidence map.
- Minimal validation experiment set.
- Failure modes and alternative branches.
Inputs
- Target context and constraints.
- Existing screen data or priors.
- Validation capabilities and throughput.
Program snapshot
Engagement: Project-based.
Output: Ranked hypotheses and validation plan.